Key result
Preload-adjusted peak power showed excellent correlation with preload-adjusted maximal power (r = 0.99, p < 0.0001) for assessing left ventricular performance.
Why the study?
Can preload-adjusted peak power act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance?
Can preload-adjusted peak power act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance?
Preload-adjusted peak power correlates excellently with preload-adjusted maximal power and can be used as a reliable substitute for assessing ventricular performance in clinical practice.
May support preload-adjusted peak power as LV performance surrogate in CABG; hypothesis-generating, needs prospective validation before adoption.
This study was performed to determine whether preload-adjusted peak power can act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance in the clinical setting. Ninety-nine consecutive patients who had undergone elective coronary artery bypass grafting were studied. Fifty-five of these patients were divided into four study groups. Afterload was changed with phenylephrine (n = 12) or glyceryl trinitrate (n = 13), preload was increased with intravenous colloid (n = 18), and contractility was increased with dobutamine (n = 12). There was excellent correlation between the two indices (r = 0.99, y = 1.0168x + 0.0769; p < 0.0001). Manipulation of neither preload nor afterload affected the indices. Both indices increased significantly during dobutamine infusion (p = 0.002). In conclusion, preload-adjusted peak power can be used as a substitute for preload-adjusted maximal power in the determination of ventricular performance in clinical practice.
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Amà et al. (2004) studied Post-coronary artery bypass grafting (n=99). Preload-adjusted peak power vs. Preload-adjusted maximal power was evaluated on Correlation between preload-adjusted peak power and preload-adjusted maximal power (r = 0.99, p=< 0.0001). Preload-adjusted peak power showed excellent correlation with preload-adjusted maximal power (r = 0.99, p < 0.0001) for assessing left ventricular performance.
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