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February 1, 2010Organic Process Research & Development251 citationsOpen Access

ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing

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CCCatherine F. CarterHLHeiko LangeSLSteven V. Ley

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Abstract

A newly developed ReactIR flow cell is reported as a convenient and versatile inline analytical tool for continuous flow chemical processing. The flow cell, operated with ATR technology, is attached directly into a reaction flow stream using standard OmniFit (HPLC) connections and can be used in combination with both meso- and microscale flow chemistry equipment. The iC IR analysis software (version 4.0) enables the monitoring of reagent consumption and product formation, aiding the rapid optimisation of procedures. Short-lived reactive intermediates can also be observed in situ, giving further mechanistic insight into complex transformations.

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Carter et al. (2010) studied this question.

synapsesocial.com/papers/6a2300b3ce88d8ac62d2741fhttps://doi.org/10.1021/op900305v
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