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Hallberg. D. Studies on the elimination of exogenous lipids from the blood stream. The kinetics for the eliminaiion of chylomicrons studied by single intravenous injections in man . Acta physiol. scand. 1965.65 . 279–284. ‐ The thoracic duct was cannulated in 2 subjects and chylomicrons were collected and then given to the subjects as rapid intravenous infusions during 2 and 5 min respectively. The amounts of triglyceride (TG) infused were 0.18 and 0.26 g/kg body weight respectively. Plasma samples were drawn and analysed for TG without and with separation into 3 fractions in a polyvinylpyrrolidone density gradient. The chylomicron TG was found in the top fraction of the gradient and endogenous plasma TG in the middle and bottom fractions. The elimination curve for the chylomicrons was found to be linear at high and exponential at low TG concentrations. During the elimination the TG concentration in the middle and bottom fractions changed in a way observed earlier for an artificial fat emulsion.
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D Hallberg (1965) studied this question.
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