SummaryThe NAIFD inhibit the release of LDH and ACPase from thrombin-aggregated platelets in vitro. They inhibit hypotonic-hyperthermic lysis of erythrocytes. The effects of NAIFD in vitro have been compared to their "anti-inflammatory" effects when given orally. A direct relationship does not exist. Of a large number of "active" and "inactive" drugs found in these and various other in vitro systems, active "anti-inflammatory" drugs appeared in both classes
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Glenn et al. (1969) studied this question.
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