Key result
High BMI variability is consistently linked to increased risk of cardiovascular outcomes, including AF and CHD.
Why the study?
High variability in BMI is recognized as a global health problem that can negatively impact the cardiovascular system, but its effect on cardiovascular risk warranted systematic review.
Does high variability in body mass index increase the risk of cardiovascular outcomes in the general population?
Systematic Review (n=7,038,873)
Does high variability in body mass index increase the risk of cardiovascular outcomes in the general population?
Fluctuations in body mass index are associated with an increased risk of incident cardiovascular events, highlighting the potential importance of maintaining weight stability in cardiovascular prevention.
Answers are grounded in this paper and cite their sources.
BMI variability monitoring should not yet alter practice; leaves open whether stabilizing weight reduces CV events.
In today's world, high variability of body mass index (BMI) is known as a significant global health problem that can lead to many negative impacts on the cardiovascular system, including atrial fibrillation (AF) and coronary heart disease. The current systematic review aims to elucidate the effect of variability in BMI on the risk of cardiovascular outcomes. Four databases, including PubMed, Scopus, MEDLINE, and CENTRAL, were searched. All related articles up to 10 June 2022, were obtained. Titles, abstracts, and full texts were reviewed. After screening abstracts and full texts, four articles were included in our study. In these four cohort studies, 7,038,873 participants from the USA and South Korea were involved. These articles generally considered the BMI and outcomes including cardiovascular disease, AF, and coronary heart disease. All these articles reported an association between the variability of BMI and increased risk of cardiovascular outcomes. Due to the negative impact of the high variability of BMI on the risk of cardiovascular outcomes, health policymakers and practitioners should pay more attention to the significant role of BMI in health problems and physicians might better check the variability of BMI visits to visit.
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Esfandiari et al. (2024) conducted a systematic review in Cardiovascular risk (n=7,038,873). Variability in Body Mass Index vs. Low or no variability in Body Mass Index was evaluated on Cardiovascular outcomes (including atrial fibrillation, coronary heart disease morbidity, and hospitalization due to cardiovascular disease). High variability of body mass index is consistently associated with an increased risk of cardiovascular outcomes, including atrial fibrillation and coronary heart disease.
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