The dependence of RBE on dose appears to follow a simple relation for a variety of effects on higher organisms and for a broad range of doses. The data indicate that the biological effects are due to primary lesions that may be produced by one or two high LET particles but require the action of at least two electrons when electromagnetic radiation is applied. The interaction distance exceeds 1 μm.
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Kellerer et al. (1971) studied this question.
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