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Correlation explores collagenase activity and arthritis severity in femoral head samples, suggesting key disease insights.
Articular cartilage collagenase activity was determined for 28 sections obtained from twelve femoral heads. For each one square centimeter area, a section was graded by a histologic-histochemical grading system for the severity of the arthritis. Collagenase activity was found primarily in those areas of moderately severe disease, but not in mild or end stage arthritis.
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Ehrlich et al. (1978) studied this question.
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