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Under the assumptions of the neutral infinite alleles model, K (the total number of alleles present in a sample) is sufficient for estimating θ (the mutation rate). This is a direct result of the Ewens sampling formula, which gives a consistent, asymptotically normal estimator for θ based on K . It is shown that the same estimator used to estimate θ under neutrality is consistent and asymptotically normal, even when the assumption of selective neutrality is violated.
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Paul Joyce (1995) studied this question.
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