Water-soluble species can be deposited into preformed, multilayered polyelectrolyte capsules, templated onto melamine formaldehyde particles, with high integrity. Efficient encapsulation of albumin within capsules formed from a poly(styrene sulfonate)/poly(allylamine hydrochloride) composite was achieved at pH values below the isoelctric point of the protein through spontaneous deposition (see picture).
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Gao et al. (2002) studied this question.
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