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September 15, 2003Journal of Clinical Investigation159 citationsOpen Access

CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis

DSDavid SanchoMGManuel Gómez‐FloritFVFernando Viedma

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Abstract

tions In addition, NK cell-dependent tumor rejection is favored in the absence of CD69 (13). However, the functional role of CD69 expressed by T cells and macrophages at inflammatory sites and in autoimmune processes has not been explored.

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Sancho et al. (2003) studied this question.

synapsesocial.com/papers/6a23a6c21c36a2d27b9ee026https://doi.org/10.1172/jci200319112
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Also Consider

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  1. 1The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis1988 · 19,988 citations
  2. 2Antagonistic and agonistic effects of transforming growth factor-beta and IL-1 in rheumatoid synovium.1990 · 114 citations
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  4. 4Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens.1986 · 246 citations
  5. 5Enhanced Antitumor Immunity in Mice Deficient in CD692003 · 173 citations