Impact of Lipid Status on Environmental Quality of Life and Mood Disorders Among Diabetic Cohorts

Introduction: Diabetes Mellitus (DM) and dyslipidaemia are few of the most common related illnesses significantly contributing to cardiovascular risk. Upcoming evidence shows that psychiatric morbidity and Quality of Life (QoL) can be influenced by metabolic disturbances. Our present study aims to assess the association between lipid levels, mood disorders, and QoL among patients with chronic T2DM in a tertiary care setting. Materials and Methods: This cross-sectional study was done among 50 individuals diagnosed with Diabetes Mellitus with a minimum duration of five years. The study was done at a tertiary care centre in Coimbatore, Tamilnadu. Institutional Human Ethics Committee approval was sought before the start of the study, and written informed consent was obtained from all the participants. Sociodemographic and clinical details were recorded; lipid levels were used to categorize participants into dyslipidaemia and normal lipid groups. The M.I.N.I. Plus 5.0 structured diagnostic interview was used to assess psychiatric co morbidities. Quality of Life was evaluated using the WHOQOL-BREF questionnaire. Results: Dyslipidaemia was seen in 68% of the study group. Although patterns of mood disorders varied between groups, the association between lipid status and psychiatric diagnosis was not statistically significant (P = 0.068). A significant difference was seen in the Environmental domain of QoL (P = 0.018), with lower scores reported in dyslipidaemia patients. Conclusion: Dyslipidaemia impacts the environmental dimension of Quality of Life to a significant extent among diabetics, underlining the need for integrated metabolic and psychosocial care.