Unactivated Photoredox C–H Amination with Diazirines: Access to Acyldiaziridines

A metal-free, photoinduced amination of unactivated C-H bonds from abundant, simple alkanes with diazirines is reported. The transformation provides diversifiable diaziridine products (40 examples) in up to 95% yields. The conditions are suitable for four different classes of C-H bonds, including aldehydes, which results in the formation of previously unavailable acyldiaziridines. This class of molecules is shown to consist of versatile precursors that are easily converted into amides, hydrazides, acyl hydrazones, and heterocycles.