Editorial for Special Issue “Biemann: Embracing the Unknown”

was the recipient of the 2024 ASMS Biemann Medal for his groundbreaking contributions to the field of metabolomics.His work has transformed how researchers study metabolism in complex biological systems.This award recognizes several major advances driven by Gary's group, including (1) "credentialing" mass spectrometry ions of biological relevance;(2) developing innovative techniques to map the fate of isotopically labeled nutrients; (3) tracing metabolites exchanged between neighboring cells and tissues in vivo; and (4) leadership in establishing rigorous best practices for metabolomics data quality, annotation, and reproducibility.Gary earned his B.A. in Chemistry and Philosophy and his Ph.D. in Biological Chemistry under the mentorship of Professor Jacob Schaefer, where he focused on utilizing advanced NMR spectroscopic techniques to study bacterial metabolism.Gary then conducted a postdoctoral fellowship at the Scripps Research Institute in Prof. Gary Siuzdak's laboratory.There, Gary demonstrated the application of metabolomics to complex human diseases and contributed to the development of widely used informatics resources in metabolomics such as the METLIN metabolite database and