(872) Clinical Predictors of Postoperative Pain Following Penoscrotal Inflatable Penile Prosthesis Implantation with HESO Reservoir Placement

Introduction Postoperative pain is a key determinant of patient satisfaction and early recovery following penile prosthesis implantation (PPI). Hamdan extrainguinal sub-oblique (HESO) reservoir placement technique was developed to enhance safety and minimize postoperative discomfort. However, predictors of pain outcomes in patients undergoing penoscrotal PPI with HESO placement remain underexplored. Objective To identify clinical and demographic predictors of moderate-to-severe postoperative pain following penoscrotal inflatable penile prosthesis (IPP) implantation with HESO reservoir placement. Methods A Prospective analysis was conducted on 152 patients who underwent penoscrotal IPP implantation using the HESO technique. Postoperative pain was assessed on a numeric rating scale (1–10). Significant pain was defined as >5/10. Univariate and multivariable logistic regression analyses were performed including age, body mass index (BMI), diabetes mellitus (DM), hypertension (HTN), and history of pelvic surgery as predictors. Results The mean pain score at rest was 4.6 ± 2.2, and with movement/coughing 5.6 ± 2.2. Pain localization was most frequent at the reservoir site (62.8%), followed by the penile shaft (25.6%) and scrotum (15.1%). In multivariable analysis, older age was independently associated with lower odds of significant postoperative pain (OR = 0.94; 95% CI 0.88–0.99; p = 0.03). BMI, DM, HTN, and prior pelvic surgery were not significantly correlated with pain outcomes. Conclusions Older patients experienced less postoperative pain following penoscrotal IPP with HESO reservoir placement. Pain was most localized to the reservoir site. Age-related physiological and perceptual factors may influence postoperative pain sensitivity, while BMI and comorbidities exert limited effect. Disclosure No