Long-Term Lesion Progression After Left Main Distal Bifurcation Stenting: Insights From Bifurcation Angle Variation Throughout the Cardiac Cycle.

Background: and the related impact on lesion progression in patients undergoing single- or dual-stenting. Methods: ) bifurcation angles were quantified throughout the cardiac cycle using two-dimensional quantitative coronary angiography at optimal views before the procedure, immediately after, and at long-term follow-up. These measurements represented the absolute difference between the end-diastolic and end-systolic angles for the left main (LM) to the left circumflex (LCX) and for the left anterior descending (LAD) to the LCX. Lesion progression was assessed from increases in diameter stenosis percentage (iDS%) from post-procedure to follow-up. Results: correlated linearly with the iDS%-LCX metric in the dual stenting. Conclusions: represents an independent anatomical risk marker for future LCX progression in patients with dual-stented LMCBLs.