An intelligent responsive nanoplatform based on a DNA nanoflowers/Mn:CuS hybrid for targeted and synergistic cancer therapy

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Key Points

The aim is to design and evaluate a hybrid nanoplatform for targeted and effective cancer therapy.
Developed a nanoplatform combining doxorubicin with Mn:CuS and DNA nanoflowers.
Evaluated efficacy in targeted cancer therapy through schematic design and assembly.
Focused on synergistic effects of combined treatment approaches.
Hybrid platform demonstrated increased targeting ability compared to traditional therapies.
Synergistic effects observed, enhancing therapeutic outcomes in clinical models.
Targeted delivery improved the efficacy of doxorubicin in cancer treatment.

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Investigates targeted cancer therapy effectiveness using a DNA nanoflowers hybrid, suggesting improved outcomes.

A schematic illustration of the design and assembly of DOX@Mn:CuS@DNA-NFs for targeted and synergistic cancer therapy.

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Zhang et al. (2026) studied this question.

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