Case report shows eculizumab improves thrombotic microangiopathy in a child with SLE, suggesting effective treatment.
Thrombotic microangiopathy (TMA) is a rare but serious complication of systemic lupus erythematosus (SLE) in children, which is often resistant to different medical treatments. This is the report of a 13 years old female with a newly diagnosed SLE, complicated with a refractory course of SLE-TMA. Eculizumab had an effective therapeutic impact with clinical and laboratory improvement of TMA.
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Nickavar et al. (2026) studied this question.
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