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June 4, 2026The Journal of Dermatology

Juvenile‐Onset SAPHO Syndrome With Acne‐Hidradenitis Suppurativa Successfully Treated With Infliximab and Methotrexate

Keiko Manabe Moe Tokunaga Shoichi Nawachi Yoshia Miyawaki Takayuki Katsuyama Yoshinori Matsumoto Mitsuru Tsuge Yoshio Kawakami Shin Morizane

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Key Points

The aim is to present a case of juvenile-onset SAPHO syndrome and its successful treatment.
Administered infliximab and methotrexate to treat the patient.
Monitored clinical outcomes and response to treatment.
Patient showed significant improvement in symptoms.
Both infliximab and methotrexate contributed to effective management of acne and hidradenitis suppurativa.

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Implication

Case report demonstrates effective treatment of juvenile-onset SAPHO syndrome with infliximab and methotrexate, highlighting potential therapies.

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Cite This Study

Manabe et al. (2026) studied this question.

synapsesocial.com/papers/6a23bb7971a5da9775e76ea0 https://doi.org/10.1111/1346-8138.70325

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