Randomized trial investigates green tea's role in managing oxidative stress and intestinal health in rats, suggesting its potential in obesity prevention.
Key Points
This study aims to determine how green tea impacts obesity and its related metabolic disorders in rats on a high-fat diet.
24 Wistar rats divided into 4 groups for diet comparison over 16 weeks.
Groups received either a standard diet, standard diet with green tea, high-fat diet, or high-fat diet with green tea.
Biochemical and oxidative analyses were performed on plasma and tissues, including gut microbiota assessment.
High-fat diet led to a 19% increase in body weight and 156% increase in adipose tissue weight.
Green tea supplementation decreased body weight by 16% and adipose tissue mass by 48% in the high-fat group.
Green tea restored blood glucose levels by 35% and triglyceride levels by 11%, while enhancing antioxidant levels and modifying gut microbiota.