Formal cardiac rehabilitation programs, which issue individual exercise prescriptions based on exercise testing, had a significantly lower incidence of adverse events compared to non-formal programs (5.04 vs 34.16 events per 100,000 patient-hours, P<0.001).
Observational
Yes
Absolute Event Rate: 5.04% vs 34.16%
p-value: p=<0.001
BACKGROUND: The safety of exercise-based cardiac rehabilitation (CR) has not been investigated in Japan, so a nationwide survey was conducted to investigate the incidence of adverse events (AEs) associated with CR and exercise testing. METHODS AND RESULTS: In total, 136 hospitals reported operating recovery-phase CR programs, amounting to 383,096 patient-hours of exercise training. The incidence rates of all AEs and life-threatening AEs (LAE: death, cardiac arrest, acute myocardial infarction, cardiac rupture) during exercise sessions were 12 and 1 event/383,096 patient-hours (3.13 and 0.26 events/100,000patient-hours), respectively. When CR programs were categorized as "Formal" in which an exercise prescription based on exercise testing was issued to individual patients or "Non-formal" without exercise prescription, the incidence of AEs during and within the 24 h after an exercise session was significantly lower in the Formal than the Non-formal CR programs (P<0.001), despite similar hospital size and coronary intervention volumes between the 2 category hospitals. Moreover, LAEs did not occur in 277,721 patient-hours in Formal CR, whereas 2 LAEs occurred in 105,375 patient-hours in Non-formal CR (P<0.05). During 469,215 exercise testing sessions, 3 LAEs (0.64 event/100,000tests) and 31 non-LAEs (6.61 events/100,000tests) occurred. CONCLUSIONS: This first nationwide survey in Japan revealed that both exercise-based CR and exercise testing are generally safe, and that Formal CR, in which an individual exercise prescription is determined by exercise testing, is particularly safe.
Saito et al. (Wed,) conducted a observational in Cardiac disease. Formal cardiac rehabilitation vs. Non-formal cardiac rehabilitation was evaluated on Incidence of adverse events during and within 24 hours after an exercise session (per 100,000 patient-hours) (p=<0.001). Formal cardiac rehabilitation programs, which issue individual exercise prescriptions based on exercise testing, had a significantly lower incidence of adverse events compared to non-formal programs (5.04 vs 34.16 events per 100,000 patient-hours, P<0.001).