August 26, 2006Journal of the American Chemical Society184 citations
View Full PaperSynthesis of Indenyl Ethers by Gold(I)-Catalyzed Intramolecular Carboalkoxylation of Alkynes
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Abstract
The gold(I)-catalyzed carboalkoxylation of alkynes to form indanone derivatives from readily available ortho-acetylenic benzylic ethers is described. Importantly, the gold(I)-catalyzed rearrangement of enantioenriched benzylic ethers proceeds with chirality transfer, thus providing a practical method for the enantioselective synthesis of indenyl ethers.