March 12, 1985Biochemistry

Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)

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Population

Human low-density lipoproteins isolated from single donors and rat very low density lipoproteins isolated…

Design

Preclinical

Authors

JEJohn ElovsonUnited States Department of Veterans Affairs JJJames C. Jacobs VSVerne N. SchumakerUniversity of California, Los Angeles

Discussion

Member takes

Implication

Provides reference molecular weights for apoprotein B; leaves open translation to human cardiovascular risk.

Structured PICO

Population

Human low-density lipoproteins (LDL) isolated from single donors and rat very low density lipoproteins (VLDL) isolated from sera of Triton WR1339 treated animals

Intervention

Biochemical analysis including sedimentation, diffusion, Sepharose chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

Outcome

Molecular weight of human apoprotein B-PI and rat apoprotein B-PIIIsurrogate

This basic science study establishes the molecular weights of human apoprotein B-PI (387,000) and rat apoprotein B-PIII (210,000) using multiple biochemical techniques.

Cite This Study

Elovson et al. (1985) studied this question.

synapsesocial.com/papers/6a247998d753e03433862d91 https://doi.org/10.1021/bi00327a042

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Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider