Key result
Percutaneous pulmonary valve implantation using the Melody valve successfully reduced right ventricular outflow tract pressure gradients in two young men with degenerated conduits.
Why the study?
RV-PA conduits used in surgical repair of congenital heart defects frequently stenose or develop insufficiency over time, necessitating reoperations that percutaneous pulmonary valve implantation can delay.
Does percutaneous pulmonary valve implantation improve haemodynamics in patients with congenital heart defects and degenerated RV-PA conduits?
Case Report (n=2)
No
Does percutaneous pulmonary valve implantation improve haemodynamics in patients with congenital heart defects and degenerated RV-PA conduits?
Percutaneous pulmonary valve implantation using the Melody valve provides an effective, less invasive alternative to repeat open-heart surgery for patients with congenital heart disease and degenerated RV-PA conduits, yielding good immediate haemodynamic improvements.
Right ventricle to pulmonary artery (RV-PA) conduits have been used for the surgical repair of congenital heart defects. These conduits frequently become stenosed or develop insufficiency with time, necessitating reoperations. Percutanous pulmonary valve implantation (PPVI) can delay the need for repeated surgeries in patients with congenital heart defects and degenerated RV-PA conduits. We presented our first experience with PPVI and described in detail the procedural methods and the considerations that are needed for this intervention to be successful. Immediate and short-term clinical outcomes of our patients were reported. Good haemodynamic results were obtained, both angiographically and on echocardiography. PPVI provides an excellent alternative to repeat open-heart surgery for patients with congenital heart defects and degenerated RV-PA conduits. This represents a paradigm shift in the management of congenital heart disease, which is traditionally managed by open-heart surgery.
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Tay et al. (2018) conducted a case report in Congenital heart disease with degenerated right ventricle to pulmonary artery conduits (n=2). Percutaneous pulmonary valve implantation (Melody valve) was evaluated on Hemodynamic improvement (RVOT peak gradient reduction). Percutaneous pulmonary valve implantation using the Melody valve successfully reduced right ventricular outflow tract pressure gradients in two young men with degenerated conduits.
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