What is the clinical evidence from this study?

Study design: Observational. Population: Type 2 diabetes. Intervention: Demographic factors (age, sex, race/ethnicity). Primary outcome: Incident type 2 diabetes per 100,000 persons per year.

What does this research mean for the field?

Type 2 diabetes incidence in U.S. youth and young adults is high, with disproportionately higher rates observed among older age groups, non-Hispanic Black, and Hispanic populations. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

The research aims to estimate the incidence of type 2 diabetes among youth and young adults using electronic health data.

June 7, 2026Diabetes

2329-P: Type 2 Diabetes Incidence in Youth and Young Adults Aged 10–44 in the Diabetes in Children, Adolescents, and Young Adults Network (DiCAYA) Study, 2018–2023

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Key result

Young adults exhibit up to an ~8-fold higher incident T2D rate compared to youth.

Why the study?

Type 2 diabetes incidence has been increasing among youth, prompting the estimation of incidence among youth and young adults using multiple electronic health record networks.

Key Points

The research aims to estimate the incidence of type 2 diabetes among youth and young adults using electronic health data.
Utilized the DiCAYA network covering six health systems and two geographic centers in the U.S.
Identified incident T2D using ICD-10 diagnosis codes from electronic health records between 2018-2023.
Calculated incidence rates by age, sex, and race/ethnicity.
T2D incidence rates for youth (10-17 years) were 29.2 per 100,000 in geographic centers and 39.8 in health systems.
Young adults (18-44 years) showed rates of 195.0 in geographic centers and 326.8 in health systems.
Incidence rates increased with age, with higher rates observed in non-Hispanic Black and Hispanic groups.

Study Design

Type

Observational

Multicenter

Yes

Structured PICO

Population

Youth aged 10-17 and young adults aged 18-44 in the United States evaluated for incident type 2 diabetes using electronic health records from 2018-2023.

Outcome

Incident Type 2 diabetes (T2D) identified using first-time ICD-10 diagnosis codes in 2018-2023

The study highlights a high incidence of Type 2 diabetes among U.S. youth and young adults, with rates increasing with age and disproportionately affecting non-Hispanic Black and Hispanic populations.

Limitations

The magnitude of incidence rates varied by the type of EHR network (geographic centers vs. health systems).

Discussion

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Implication

These rates support enhanced surveillance in youth and young adults; extends prior U.S. incidence estimates with recent multi-system data.

Cite This Study

Mefford et al. (2026) conducted an observational in Type 2 diabetes. Demographic factors (age, sex, race/ethnicity) was evaluated on Incident type 2 diabetes per 100,000 persons per year. Incident type 2 diabetes rates were 29.2 to 39.8 per 100,000 person-years among youth aged 10-17, and 195.0 to 326.8 per 100,000 person-years among young adults aged 18-44.

synapsesocial.com/papers/6a250b2d7def13d035e1b381 https://doi.org/10.2337/db26-2329-p

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Implication

These rates support enhanced surveillance in youth and young adults; extends prior U.S. incidence estimates with recent multi-system data.

2329-P: Type 2 Diabetes Incidence in Youth and Young Adults Aged 10–44 in the Diabetes in Children, Adolescents, and Young Adults Network (DiCAYA) Study, 2018–2023

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

2329-P: Type 2 Diabetes Incidence in Youth and Young Adults Aged 10–44 in the Diabetes in Children, Adolescents, and Young Adults Network (DiCAYA) Study, 2018–2023

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider