2332-P: Baseline Characteristics of Young Adults with New-Onset Type 2 Diabetes and Their Glycemic Control after One-Year Follow-Up in PHC Units in Mexico (2014-2025)

Introduction and Objective: T2D in young adults often follows a more aggressive clinical course compared with older populations. The objective of this study was to describe the baseline characteristics of young adults with new-onset T2D and evaluate their glycemic control after one-year of follow-up in PHC units in Mexico. Methods: We conducted an observational, descriptive, cross-sectional study using data from the national Chronic Disease Information System (SIC) to identify adults aged 18-30 years with new-onset T2D between January 2014 and November 2025. Baseline characteristics and HbA1c levels (controlled <7%, uncontrolled 7-8.9%, severely uncontrolled 9-11.9%, critically uncontrolled ≥12%) were recorded at diagnosis and after one-year of follow-up. Results were compared using χ² tests. Results: A total of 668 young adults were identified, from which 78.7% were females. Their mean age was 26.2 years. Family history of TD2 was common (61.4%). Comorbidities were highly prevalent (67.1%). Although 54.9% had HbA1c ≥7%, early insulinization was initiated in only 37.9%. After one-year of follow-up, glycemic control was highly unstable. Among patients with HbA1c <7%, 62.1% lost glycemic control. Among those initially classified as uncontrolled and severely uncontrolled, 40.0% and 14.1% progressed to more critical glycemic levels. Notably, 69.8% of the patients initially classified as critically uncontrolled remained the same, suggesting substantial therapeutic inertia. Conclusion: Young adults with new-onset T2D have a high burden of comorbidities and require early insulinization. Early glycemic control was highly unstable, and severe hyperglycemia persisted in most patients despite ongoing care, highlighting the urgent need for intensified management and targeted interventions in this high-risk population.