Pd-Catalyzed Stereoselective Enol Ether Coupling toward C2-Branched Carbohydrates: Experimental and Computational Insights into Glycal-Controlled Diastereoselectivity

C2-branched glycal derivatives are key structural motifs in numerous pharmaceuticals and biologically active molecules. Herein, we report a ligand-free, palladium-catalyzed stereoselective cross-coupling of readily accessible iodo-glycals with cyclic enol ethers,...