2260-P: Diabetes Distress in Dialysis Patients: A Substudy of the NIH CONDOR Trial

Introduction and Objective: There is a high burden of diabetes among dialysis patients, among whom the combined burden of diabetes and ESKD management may adversely impact their self-care behaviors, treatment adherence, and glycemic control. Using a validated survey, we evaluated the burden of diabetes distress in a substudy of the NIH “Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia (CONDOR)” Trial. Methods: In a subcohort of 32 hemodialysis patients with diabetes from the NIH CONDOR trial, we administered the Diabetes Distress Scale-17 (DDS-17), a validated 17-item survey to assess diabetes-specific distress across 4 domains of emotional burden, regimen-related distress, physician-related distress, and interpersonal distress, at study entry. Results: Baseline DDS-17 scores showed that 63% (N=20) patients demonstrated “little or no distress” (total score <2.0), 34% (N=11) patients demonstrated “moderate distress” (total score 2.0-2.9), and 3% (N=1) patient demonstrated “high diabetes-related distress.” Conclusion: There is a wide variation in diabetes-related distress among dialysis patients with diabetes, with a sizeable proportion reporting moderate distress. Future studies are needed to clarify the determinants and impact of diabetes distress on clinical outcomes to better inform targeted interventions that improve diabetes care in this high-risk population. Disclosure C. Rhee: None. A. Daza: None. Y. Narasaki: None. D. Nguyen: None. K. Kalantar-Zadeh: Consultant; Current; Fresenius Medical Care. Funding NIH (R01DK132869)