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June 7, 2026Journal of Applied MathematicsOpen Access

Mathematical Modeling of Leptospirosis With Misdiagnosis

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Authors

JMJapheth Musingila MwongelaCKCaroline KanyiriVKVirginia Kitetu

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Overview

Randomized trial examines impact of misdiagnosis on leptospirosis transmission dynamics, suggesting better diagnostics can improve control.

Key Points

  • This study aims to analyze the impact of misdiagnosis on leptospirosis transmission dynamics using a mathematical model.
  • Developed a compartmental epidemic model incorporating disease progression, treatment, and misdiagnosis pathways.
  • Analyzed the model for positivity, boundedness, equilibrium points, and stability.
  • Conducted numerical simulations using MATLAB to support analytical results.
  • Increased rates of misdiagnosis raised the effective reproduction number significantly.
  • Accelerated disease spread was observed with higher misdiagnosis rates.
  • Diagnostic accuracy is crucial for control measures, as misdiagnosis undermines treatment effectiveness.

Cite This Study

Mwongela et al. (2026) studied this question.

synapsesocial.com/papers/6a250bca7def13d035e1bd73https://doi.org/10.1155/jama/5513951
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