Key result
Co-existing obesity, diabetes, and CVD linked to ~250% higher annual healthcare costs versus unaffected adults.
Why the study?
Diabetes, obesity, and cardiovascular disease frequently co-occur, but medical costs associated with these conditions individually and jointly required estimation.
Cross-Sectional
Absolute Event Rate: 23262% vs 6576%
Co-existing diabetes and cardiovascular disease significantly increase annual healthcare expenditures, an effect further amplified by obesity.
Introduction and Objective: Diabetes, obesity, and cardiovascular disease (CVD) often co-occur. This study estimated medical costs associated with diabetes, obesity, and CVD individually and jointly. Methods: We analyzed pooled 2016, 2018, 2020, and 2022 Medical Expenditures Panel Survey data. Annual health care costs (adjusted to 2022 U.S. dollars) were modeled using gamma generalized linear models adjusted for demographic and health characteristics. BMI was dichotomized as obesity (BMI ≥30 kg/m²) and without obesity (BMI 18.5-29.9 kg/m²). Diabetes and CVD were defined as self-report of ever receiving a diagnosis. CVD included coronary heart disease, angina, myocardial infarction, stroke, and other heart disease. Incremental expenditures related to co-occurring comorbidities were calculated using model coefficients and interaction terms between comorbidities. Results: In adults without obesity, costs rose from $6,576 (no additional comorbidities, 56% of population) to $12,181 with diabetes (4%), $12,846 with CVD (4%), and $19,904 with both diabetes and CVD (2%). Among adults with obesity, costs rose from $7,203 (no diabetes or CVD, 25%) to $12,906 with diabetes (5%), $15,937 with CVD (2%), and $23,262 with both (2%). Costs increase with more conditions. Conclusion: The higher expenditure observed for co-existing diabetes and CVD could be amplified by obesity. Prevention, early screening and integrated management may reduce substantial economic burden. Disclosure P. Zhang: None. H. Shao: None. K. Bullard: None. R. Li: None. Y. Wang: None.
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ZHANG et al. (2026) conducted a cross-sectional in Diabetes, obesity, and cardiovascular disease. Co-occurring diabetes, obesity, and cardiovascular disease vs. No obesity, diabetes, or cardiovascular disease was evaluated on Annual health care costs. Co-existing obesity, diabetes, and cardiovascular disease was associated with the highest annual healthcare costs ($23,262) compared to adults without any of these conditions ($6,576).
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