Forum article highlights microbial links, mucin biology, and tumor behavior in pseudomyxoma peritonei, suggesting future research needs.
Pseudomyxoma peritonei is a rare, heterogeneous appendiceal cancer characterized by mucus-secreting tumor cells. Evidence suggests a microbial association, though its significance remains unclear. This forum article synthesizes links among microbial communities, mucin biology, and tumor behavior, highlighting key research challenges and how spatial multiomics may clarify disease mechanisms and therapeutic opportunities.
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Grant et al. (2026) studied this question.
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