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Report highlights rare cases of radiation-induced gliomas in patients treated for leukemia and tinea capitis, suggesting potential genetic links.
Radiation-induced gliomas are uncommon, with only 73 cases on record to date. The disease that most frequently occasioned radiation therapy has been acute lyrnphoblastic leukemia (ALL). Three more cases are added here, two after irradiation for ALL and one after irradiation for tinea capitis. In a review of the relevant literature, the authors stress the possibility that the ALL-glioma and the retinoblastoma-glioma links point to syndromes in their own right that may occur without radiation therapy.
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Salvati et al. (1991) studied this question.
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