Four patients who were suffering from typical lichen amyloidosus were treated with etretinate (Tigason®). Itching was relieved in all cases within 2 weeks. The lesions were completely cleared in three cases within 10-20 weeks and markedly improved in one case. No amyloid material could be detected in skin biopsies taken after the treatment period of several months. No immediate relapses were observed after discontinuation of the etretinate treatment.
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Helander et al. (1986) studied this question.
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