Abstract Warthin-like papillary thyroid carcinoma (WL-PTC) is a rare subtype of papillary thyroid carcinoma, defined by oncocytic cells with typical papillary thyroid cancer nuclear features and dense lymphocytic infiltration. Despite its rarity, it usually has a favourable prognosis. A retrospective case series of six patients diagnosed between January 2020 and November 2024 was reviewed, including clinical, imaging, cytology, surgical, histopathological, and follow-up data. The group consisted of five females and one male, with age of patients ranged from 23 to 54 years. Patients presented with thyroid or neck nodules, localised pain, or systemic symptoms. All underwent total thyroidectomy, and three also had lymph node dissections, with two cases showing nodal metastasis. Histopathological examination confirmed WL-PTC, either alone or alongside conventional papillary thyroid carcinoma. No recurrence or residual disease was detected during follow-up, and thyroglobulin levels remained normal. WL-PTC should be accurately identified in pathology reports, and further research is needed to clarify its long-term biological behaviour.
Salih et al. (Wed,) studied this question.