Discussion proposes revisions to adverse drug reactions forms to improve reporting of withdrawal reactions in pharmacovigilance.
Pharmacovigilance plays a crucial role in post-marketing surveillance of medicines and relies on the spontaneous reporting of adverse drug reactions (ADRs). Discontinuation of a drug can cause clinically relevant signs and symptoms, including withdrawal reactions; however, this subset of ADRs is not fully accommodated in current pharmacovigilance practice. We discuss proposed revisions to current ADR forms that could enhance the capture of withdrawal reaction evidence.
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Khan et al. (2026) studied this question.
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