Delayed Methicillin-resistant Staphylococcus aureus Infection Following Trigger Finger Release in the Setting of Anti-Interleukin-5 Therapy: A Case Report

We report a rare case of delayed methicillin-resistant Staphylococcus aureus (MRSA) infection following elective mini-open trigger finger release in a 55-year-old male with asthma receiving anti-interleukin (IL)-5 therapy. The patient initially recovered uneventfully but developed signs of infectious flexor tenosynovitis on postoperative day 36. Culture confirmed MRSA, and surgical debridement was required. The patient continued anti-IL-5 therapy throughout the perioperative period. Although a causal relationship cannot be established, this case raises awareness of a potential association between biologic therapy and delayed postoperative infection.