What question did this study set out to answer?

This study examines the relationship between GLP-1 receptor agonist use and postoperative complications during ambulatory eye surgery.

Perioperative Desaturation and Postoperative Nausea or Vomiting Requiring Antiemetic Administration in Glucagon‐Like Peptide‐1 Receptor Agonist Users Undergoing Ambulatory Ophthalmic Surgery Under Mild‐To‐Moderate Sedation: A Large Retrospective Cohort Study

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Retrospective cohort study explores PONV effects in GLP-1RA users during outpatient surgery, suggesting careful management.

This study examines the relationship between GLP-1 receptor agonist use and postoperative complications during ambulatory eye surgery.
Retrospective observational cohort study of adults undergoing mild-to-moderate sedation eye surgeries.
Patients classified as GLP-1RA users or non-users with outcomes assessed using logistic regression.
Data sourced from 45,636 visits from January 2022 to December 2024.
GLP-1RA use did not increase desaturation events (OR 1.22, 95% CI 0.38–3.88, p=0.74).
GLP-1RA users had a higher incidence of postoperative nausea or vomiting requiring antiemetics (OR 1.93, 95% CI 1.29–2.89, p=0.001).
No aspiration events were reported in either group during the study period.

Hyung et al. (2026) studied this question.

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