Computational Analysis of Particulate Dispersion and Environmental Purity in an ISO Class 5 Cleanroom

This research employs numerical simulation techniques to examine the dispersion behavior of indoor contaminants and the sustained cleanliness performance of an ISO Class 5 cleanroom across varying personnel density (6, 18, and 36 occupants). A computational model was developed to replicate particle emission from personnel and their subsequent extraction by the ventilation system. Findings demonstrate that the configured airflow effectively controls and removes pollutants under all cases. Following the termination of particle release, contaminant levels diminish to negligible concentrations within 30 seconds. Assessment based on particle count metrics confirms that critical zones comply with the ISO Class 5 standard under every operational condition. The number of occupants, within the studied range, showed no substantial influence on the cleanliness of the principal working area. This work offers valuable insights for the design and performance validation of analogous cleanliness controlled environments.