Genome-wide characterization identifies 17 m6A regulatory genes in Ginkgo biloba, suggesting roles in gene regulation and stress response.
m6A is an important RNA modification involved in post-transcriptional regulation in plants. However, putative m6A writers and erasers in G. biloba remain poorly characterized. In this study, a total of 17 candidate m6A regulatory genes, including 8 writers and 9 erasers, were identified through genome-wide analysis. Phylogenetic and structural analyses indicated that these proteins are generally conserved, with some members showing potential functional divergence. Promoter analysis revealed abundant hormone- and stress-responsive cis-elements, and expression profiling showed tissue-specific patterns and dynamic responses to ABA, MeJA, and NaCl treatments, with erasers exhibiting greater transcriptional responsiveness than writers. In addition, protein interaction network and phase separation predictions suggested potential roles in RNA methylation-related processes. These results provide a foundation for further functional studies of m6A regulation in G. biloba.
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Ma et al. (2026) studied this question.
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