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June 10, 2026Case Reports in Critical CareOpen Access

Heat Stroke Encephalopathy Without the Presence of Distinct Imaging Findings: Case Report and Review of Literature

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Authors

RSRyan SholesDWDavid J. WalzJEJulia Evans

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Overview

Case report reveals persistent encephalopathy in heat stroke without clear imaging abnormalities, suggesting diagnostic challenges.

Key Points

  • To illustrate a case of severe encephalopathy following heat stroke without distinct neuroimaging findings.
  • Described a case of a 72-year-old man with heat stroke and unresponsive behavior found in a vehicle.
  • Evaluated the patient with comprehensive metabolic, infectious, and toxicologic assessments.
  • Performed electroencephalography and brain MRI after hospitalization.
  • Patient maintained a Glasgow Coma Scale score of 5 upon arrival despite cooling interventions.
  • MRI showed no acute abnormalities, only mild age-related atrophy and chronic ischemic changes.
  • Ultimately, the patient's neurological function did not recover, leading to death on Day 27.

Cite This Study

Sholes et al. (2026) studied this question.

synapsesocial.com/papers/6a28ff956f82f25be989c799https://doi.org/10.1155/crcc/6609879
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heat stress presenting with encephalopathy and MRI findings of diffuse cerebral injury and hemorrhage2013 · 25 citations
  2. 2Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Heat Illness: 2019 Update2019 · 93 citations
  3. 3ACSM Expert Consensus Statement on Exertional Heat Illness: Recognition, Management, and Return to Activity2023 · 102 citations
  4. 4An acute severe heat stroke patient showing abnormal diffuse high intensity of the cerebellar cortex in diffusion weighted image: A case report2009 · 16 citations