PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
June 10, 2026JAMA Neurology

Personalized Blood Pressure Targeting After Endovascular Therapy for Acute Ischemic Stroke

View Full Paper
Ask AI
Bookmark
Share

Authors

PCPol Camps-RenomMGMarina Guasch-JiménezJÁJuan Álvarez-Cienfuegos

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates a tailored blood pressure strategy's impact on outcomes in acute ischemic stroke, indicating improved results.

Key Points

  • Determine if a reperfusion-guided systolic blood pressure control strategy improves outcomes compared to standard management after endovascular therapy for stroke.
  • Multicenter, prospective, randomized, open-label clinical trial
  • Participants assigned to either a reperfusion-guided BP strategy or guideline-recommended management
  • 90-day follow-up with functional outcomes assessed using modified Rankin Scale
  • 60.0% of the intervention group achieved favorable outcomes compared to 47.1% in the control group (absolute risk difference 13.3%; P=0.005)
  • Hemorrhagic transformation occurred in 22.3% of the intervention group versus 31.6% in the control group (OR 0.62; 95% CI 0.41-0.95)
  • No significant differences in symptomatic intracranial hemorrhage (3.5% vs 3.9%) or 90-day mortality (15.4% vs 15.6%)

Cite This Study

Camps-Renom et al. (2026) studied this question.

synapsesocial.com/papers/6a2900566f82f25be989cf5ehttps://doi.org/10.1001/jamaneurol.2026.1706
View Full Paper
Ask AI
Bookmark
Share