Key result
A 65-year-old postmenopausal woman was successfully diagnosed with rare primary angiosarcoma of the breast using multimodality imaging and treated with a modified radical mastectomy.
Why the study?
Primary angiosarcoma of the breast predominantly occurs in young patients with nonspecific imaging features, leading to frequent oversight and misdiagnosis at radiology and pathology.
Case Report (n=1)
This case highlights the rare occurrence of primary angiosarcoma of the breast in a postmenopausal woman and the utility of multimodal imaging for its diagnosis.
Answers are grounded in this paper and cite their sources.
Multimodality imaging aided diagnosis of rare primary breast angiosarcoma; leaves open standardized management strategies for this entity.
Primary angiosarcoma (PAS) of the breast is a rare malignant tumor arising from endothelial cells lining the blood vessel and accounts for 0.04% of all breast tumors. It occurs predominantly in young patients usually presenting as nonspecific imaging features and is often overlooked and misdiagnosed at radiology and pathology. Angiosarcoma prognosis is generally poor; however, surgery followed by adjuvant chemotherapy and radiotherapy improves the prognosis. We report a rare case of PAS in a 65-year-old postmenopausal woman. She was diagnosed with PAS based on typical clinical, mammography, ultrasound, and magnetic resonance imaging (MRI) features followed by core biopsy of the lesion. Our case had the unique features of enlarged vessels within and surrounding the lesion in mammography, as well as in MRI, which could be very helpful for future diagnosis of this rare PAS in postmenopausal women.
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Issar et al. (2022) conducted a case report in Primary Angiosarcoma of the Breast (n=1). Modified radical mastectomy was evaluated on Diagnosis and surgical outcome. A 65-year-old postmenopausal woman was successfully diagnosed with rare primary angiosarcoma of the breast using multimodality imaging and treated with a modified radical mastectomy.
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