This research investigates the relationship between microbial ecology and hepatocellular carcinoma, considering whether certain HCC subsets may be influenced by the microbiome.
Discussion of established parameters of hepatocellular carcinoma including cirrhosis and viral hepatitis
Analysis of microbial factors in the context of HCC
Exploration of relevance to treatment strategies
Identifies potential links between microbiome and HCC progression
Suggests implications for viewing certain HCC cases as microbiome-conditioned malignancies
Abstract
Hepatocellular carcinoma (HCC) is usually discussed in the language of cirrhosis, viral hepatitis, metabolic dysfunction, angiogenesis, and genomic instability 1. That language is correct, but...