What question did this study set out to answer?

To characterize outcomes and management of corneal perforations due to microbial keratitis and identify risk factors affecting visual prognosis.

Outcomes of corneal perforations secondary to microbial keratitis at a tertiary care center: A case series

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Retrospective case series evaluates visual outcomes in corneal perforations, suggesting risk factors and management strategies.

To characterize outcomes and management of corneal perforations due to microbial keratitis and identify risk factors affecting visual prognosis.
Retrospective case series analyzing patients treated for corneal perforation from July 2023 to July 2025.
Patients with traumatic or autoimmune causes were excluded.
Data reviewed included demographics, visual acuity, microbial culture results, and treatment modalities.
Of 23 cases, 5 were due to microbial keratitis with pathogens including Pseudomonas aeruginosa and herpes simplex virus 1.
80% of patients underwent penetrating keratoplasty, while others received various treatments like corneal gluing or medical therapy.
Final visual acuity ranged from hand motion to 20/30, with worse outcomes linked to larger perforations and preexisting ocular conditions.

Carcione et al. (2026) studied this question.

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View Full Paper

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Authors

Retrospective case series evaluates visual outcomes in corneal perforations, suggesting risk factors and management strategies.

To characterize outcomes and management of corneal perforations due to microbial keratitis and identify risk factors affecting visual prognosis.
Retrospective case series analyzing patients treated for corneal perforation from July 2023 to July 2025.
Patients with traumatic or autoimmune causes were excluded.
Data reviewed included demographics, visual acuity, microbial culture results, and treatment modalities.
Of 23 cases, 5 were due to microbial keratitis with pathogens including Pseudomonas aeruginosa and herpes simplex virus 1.
80% of patients underwent penetrating keratoplasty, while others received various treatments like corneal gluing or medical therapy.
Final visual acuity ranged from hand motion to 20/30, with worse outcomes linked to larger perforations and preexisting ocular conditions.

Carcione et al. (2026) studied this question.

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