Comment discusses mortality interpretations in mucous membrane pemphigoid, suggesting further studies are needed to clarify risks.
We highlight several considerations relevant to interpretation of mortality findings in a large French multicentre cohort study of mucous membrane pemphigoid (MMP). Potential residual confounding, reliance on all-cause mortality, heterogeneity within ENT subgroups, and limited longitudinal treatment exposure may affect interpretation of MMP-attributable mortality estimates. Further studies incorporating cause-specific mortality and more granular phenotypic characterization may help clarify mortality risk across MMP clinical subgroups.
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Ghanim et al. (2026) studied this question.
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