Study benchmarks drug discovery strategies for compound prioritization, suggesting improved efficacy.
Drug discovery requires traversing vast chemical spaces to identify compounds exhibiting favorable potency, selectivity and absorption–distribution–metabolism–excretion–toxicity (ADMET) profiles. During this process, the synthetic and assay throughput is generally markedly lower...
No takes yet. Share an insight, caveat, or question.
Mas et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: