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June 11, 2026PeerJOpen Access

Clinical characteristics of free flaps for oral and maxillofacial reconstruction: a retrospective study of 700 flaps over 3 years

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Authors

SLS LiXYXie YanpingJXJiali Xie

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Overview

Retrospective study examines clinical features and outcomes of free flaps for oral reconstruction, suggesting early intervention is critical.

Key Points

  • This study aims to investigate the clinical characteristics and management of free flaps used in oral and maxillofacial reconstruction.
  • Retrospective analysis of 689 subjects categorized into two groups: no-flap crisis (620 flaps) and flap crisis (80 flaps).
  • Demographic and clinical data, including medical costs and intraoperative blood loss, were analyzed.
  • Distribution of flap types and timing of crisis within the flap crisis group were examined.
  • Overall survival rate of free flaps was 95% (95% CI [93.4–96.6]), with a salvage rate of 49.28% (95% CI [37.2–61.4]).
  • Significant differences in postoperative length of stay, duration of surgery, medical costs, and intraoperative blood loss were noted between the two groups.
  • Within the flap crisis group, 94.20% of crises occurred within the first 84 hours, indicating early intervention helps reduce flap failure.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a2a528480c8f91e7f39e88bhttps://doi.org/10.7717/peerj.21245
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Also Consider

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  1. 1Incidence and Risk Factors for Free Flap Compromise in Head and Neck Reconstruction: A Meta‐Analysis2026
  2. 2Predicting the Timing and Cause of Microvascular Free Flap Failure2024 · 8 citations
  3. 3Complications of Free Flap Reconstruction in Maxillary and Mandibular Defects: A Systematic Review and Meta-Analysis2026 · 1 citations
  4. 4Comprehensive analysis of risk factors for flap necrosis in free flap reconstruction of postoperative tissue defects in oral and maxillofacial tumors2024 · 4 citations
  5. 5Metabolic Predictors in Risk Stratification for Oral Cavity and Oropharyngeal Cancer Patients Undergoing Free Flap Tissue Transfer: A Retrospective Study2026