What question did this study set out to answer?

This review aims to synthesize evidence on integrated antenatal service delivery models that address HIV, syphilis, and HBV simultaneously.

June 11, 2026HealthcareOpen Access

Integrated Service Delivery Models for Triple Elimination of Mother to Child Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B Virus: A Global Systematic Review and Meta-Analysis

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Authors

VAVictor Abiola AdepojuUniversity of Abuja AAAbdulrakib AbdulrahimUniversiti Putra Malaysia QAQorinah Estiningtyas Sakilah AdnaniPadjadjaran University

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Implication

Systematic review identifies integrated antenatal services improving outcomes for maternal health, suggesting significant benefits in resource-limited settings.

Key Points

This review aims to synthesize evidence on integrated antenatal service delivery models that address HIV, syphilis, and HBV simultaneously.
Systematic review and meta-analysis following PRISMA 2020 guidelines.
Data extracted from 11 studies published between January 2007 and January 2026 after screening 423 records.
Conducted random-effects meta-analysis of proportions using the DerSimonian–Laird estimator.
Pooled triple testing uptake was 97% (95% CI 92 to 100%).
Large programmes achieved over 99% coverage, significantly reducing HIV vertical transmission to below 3%.
Economic analyses indicated the initiatives were cost-effective despite challenges in treatment completion and follow-up.

Cite This Study

Adepoju et al. (2026) studied this question.

synapsesocial.com/papers/6a2a528480c8f91e7f39e8d7 https://doi.org/10.3390/healthcare14121625

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Implication

Systematic review identifies integrated antenatal services improving outcomes for maternal health, suggesting significant benefits in resource-limited settings.

Integrated Service Delivery Models for Triple Elimination of Mother to Child Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B Virus: A Global Systematic Review and Meta-Analysis

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Cite This Study

Integrated Service Delivery Models for Triple Elimination of Mother to Child Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B Virus: A Global Systematic Review and Meta-Analysis

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