What question did this study set out to answer?

This study aims to evaluate the safety and efficacy of endovascular thrombectomy in patients with large vessel occlusion stroke treated beyond 24 hours.

June 12, 2026World NeurosurgeryOpen Access

Safety and Efficacy of Endovascular Thrombectomy for Progressive Anterior Circulation Large Vessel Occlusion Stroke Treated Beyond 24 Hours: A Single-Center Retrospective Cohort Study

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This study aims to evaluate the safety and efficacy of endovascular thrombectomy in patients with large vessel occlusion stroke treated beyond 24 hours.
Retrospective analysis of 190 patients, comparing outcomes between EVT (n=52) and BMT (n=138).
Primary outcome assessed was functional independence at 90 days.
Secondary outcomes included 90-day mortality and incidence of symptomatic intracranial hemorrhage.
EVT was associated with a lower median 90-day mRS score (3 vs 4, OR=1.973, 95% CI 1.164-5.042, P=0.028).
Functional independence was higher in the EVT group (46% vs 13%, OR=5.716, 95% CI 2.724-12.003, P<0.001).
90-day mortality was significantly lower in the EVT group (12% vs 41%, OR=0.182, 95% CI 0.074-0.469, P<0.001).

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Implication

Retrospective cohort study compares endovascular thrombectomy and best medical therapy for stroke, implying better outcomes with EVT.

Cite This Study

Dong et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba20e8101cf8926f0125e https://doi.org/10.1016/j.wneu.2026.125108

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Safety and Efficacy of Endovascular Thrombectomy for Progressive Anterior Circulation Large Vessel Occlusion Stroke Treated Beyond 24 Hours: A Single-Center Retrospective Cohort Study

Key Points

Discussion

Implication

Cite This Study

Safety and Efficacy of Endovascular Thrombectomy for Progressive Anterior Circulation Large Vessel Occlusion Stroke Treated Beyond 24 Hours: A Single-Center Retrospective Cohort Study

Key Points

Discussion

Implication

Cite This Study

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