Comment on Carvalho et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis

Shinya Yamaguchi; Tadao Aikawa; Toshiki Kuno

doi:10.1007/s10554-026-03755-0

June 10, 2026The International Journal of Cardiovascular Imaging

Comment on Carvalho et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis

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The ICH E9(R1) addendum establishes a structured framework for defining estimands and sensitivity analyses to ensure alignment between clinical trial objectives, design, conduct, and statistical analysis.

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Yamaguchi et al. (2026) studied this question.

synapsesocial.com/papers/6a2bb1728101cf8926f0388f https://doi.org/10.1007/s10554-026-03755-0

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Comment on Carvalho et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis

Implication

Abstract

Discussion

Cite This Study

Comment on Carvalho et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis

Implication

Abstract

Discussion

Cite This Study

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