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June 9, 2026Neurology

Real Life Effectiveness and Tolerability of Cladribine Tablets (CladT) after Five Years of Treatment (P4-20.004)

Antonio Pato Pato José Ramón Lorenzo González Daniel Apolinar García Estévez A.M. López Real Ana Rodriguez Regal Eva Costa Arpin María Rodríguez Rodríguez Elena Alvarez Rodriguez Miguel Alberte Woodgard Marta Aguado Valcárcel Inés González Suarez José María Óscar Prieto González

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Key Points

To evaluate how effective and tolerable Cladribine Tablets are in real-life clinical settings over a five-year period.
Descriptive observational study design
Data collected from clinical practice settings
Focus on treatment outcomes after five years
Cladribine Tablets demonstrated sustained effectiveness after five years of treatment.
Tolerability was reported to be acceptable with minimal adverse effects noted.

Implication

Observational study describes effectiveness and tolerability of Cladribine Tablets in clinical practice, indicating its viability for long-term use.

Abstract

To describe the effectiveness and tolerability of CladT in a clinical practice setting after 5 years of treatment.

Discussion

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Cite This Study

Pato et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf34dfaef96ed7f055c7a https://doi.org/10.1212/wnl.0000000000215180

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Treatment Persistence of Cladribine Tablets Versus Other Oral Disease-modifying Treatments for Multiple Sclerosis: Results from Danish, Norwegian, and Swedish Registries (P10-6.015)2024
2Five-by-Five: Nationwide Real-world Outcomes after ≥Five Years of Cladribine With an Age ≥50 Subanalysis (P2-20.006)Original Research · 2026
3Patients with Multiple Sclerosis in Year 5 After Initiation of Treatment with Cladribine Tablets: Analysis of Longitudinal Prescription Data from Germany (P8-6.017)2024 · 1 citations
4Real-world experience with cladribine in the two years since treatment start: a systematic review and meta-analysis2025 · 3 citations
5Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple SclerosisNarrative Review · 2023 · 13 citations

More related papers

Real-World Safety and Effectiveness of Cladribine Tablets in Older (≥ 50 Years) Patients with Relapsing Multiple Sclerosis: Results from the “Aging” Study—A Multicenter, Single-Arm, Phase 4 Observational Study2026
Therapeutic choices and disease activity after 2 years of treatment with cladribine: An Italian multicenter study (<scp>CladStop</scp>)2024
Holistic, Long-Term Management of People with Relapsing Multiple Sclerosis with Cladribine Tablets: Expert Opinion from France2024

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